#TodaysFunFact Lindyhoppers at Savoy Ballroom, 1941 #twerking

#TodaysFunFact Lindyhoppers at Savoy Ballroom, 1941 #twerking

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Today’s #FunFact: this is an African symbol. #BatSignal #Batman #DCcomics

Today’s #FunFact: this is an African symbol. #BatSignal #Batman #DCcomics

Uzi Accident: Single Shot to the Head Killed Instructornbcphiladelphia.com
A single shot to the head killed the Arizona shooting range instructor who was accidentally shot by a 9-year-old girl learning to fire an Uzi, the coroner said Thursday.

Uzi Accident: Single Shot to the Head Killed Instructor
nbcphiladelphia.com

A single shot to the head killed the Arizona shooting range instructor who was accidentally shot by a 9-year-old girl learning to fire an Uzi, the coroner said Thursday.

I love my red shrinkage. #HappyThursday

I love my red shrinkage. #HappyThursday

By @topherpatt “#ferguson throw it back at them.” via @PhotoRepost_app

By @topherpatt “#ferguson throw it back at them.” via @PhotoRepost_app

By @aunt_flo “”…..The resultant St. John Coltrane African Orthodox Church, San Francisco is the only African Orthodox church that incorporates Coltrane’s music and his lyrics as prayers in its liturgy.” #StJohnColtrane” via @PhotoRepost_app

By @aunt_flo “”…..The resultant St. John Coltrane African Orthodox Church, San Francisco is the only African Orthodox church that incorporates Coltrane’s music and his lyrics as prayers in its liturgy.” #StJohnColtrane” via @PhotoRepost_app

:By @mvmvmxlls “Howard U family, sending prayers up to our siStar ๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™ —- shot in the head with a rubber bullet by #ferguson police at a peaceful protest for #mikebrown —- from @spookwrites with @repostapp —-” via @PhotoRepost_app

:By @mvmvmxlls “Howard U family, sending prayers up to our siStar ๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™๐Ÿ™ —- shot in the head with a rubber bullet by #ferguson police at a peaceful protest for #mikebrown —- from @spookwrites with @repostapp —-” via @PhotoRepost_app

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neurosciencestuff:

Scientists use lasers and carbon nanotubes to look inside living brains
Some of the most damaging brain diseases can be traced to irregular blood delivery in the brain. Now, Stanford chemists have employed lasers and carbon nanotubes to capture an unprecedented look at blood flowing through a living brain.
The technique was developed for mice but could one day be applied to humans, potentially providing vital information in the study of stroke and migraines, and perhaps even Alzheimer’s and Parkinson’s diseases. The work is described in the journal Nature Photonics.
Current procedures for exploring the brain in living animals face significant tradeoffs. Surgically removing part of the skull offers a clear view of activity at the cellular level. But the trauma can alter the function or activity of the brain or even stimulate an immune response. Meanwhile, non-invasive techniques such as CT scans or MRI visualize function best at the whole-organ level; they cannot visualize individual vessels or groups of neurons.
The first step of the new technique, called near infrared-IIa imaging, or NIR-IIa, calls for injecting water-soluble carbon nanotubes into a live mouse’s bloodstream. The researchers then shine a near-infrared laser over the rodent’s skull.
The light causes the specially designed nanotubes to fluoresce at wavelengths of 1,300-1,400 nanometers; this range represents a sweet spot for optimal penetration with very little light scattering. The fluorescing nanotubes can then be detected to visualize the blood vessels’ structure.
Amazingly, the technique allows scientists to view about three millimeters underneath the scalp and is fine enough to visualize blood coursing through single capillaries only a few microns across, said senior author Hongjie Dai, a professor of chemistry at Stanford. Furthermore, it does not appear to have any adverse affect on innate brain functions.
"The NIR-IIa light can pass through intact scalp skin and skull and penetrate millimeters into the brain, allowing us to see vasculature in an almost non-invasive way," said first author Guosong Hong, who conducted the research as a graduate student in Dai’s lab and is now a postdoctoral fellow at Harvard. "All we have to remove is some hair."
The technique could eventually be used in human clinical trials, Hong said, but will need to be tweaked. First, the light penetration depth needs to be increased to pass deep into the human brain. Second, injecting carbon nanotubes needs approval for clinical application; the scientists are currently investigating alternative fluorescent agents.
For now, though, the technique provides a new technique for studying human cerebral-vascular diseases, such as stroke and migraines, in animal models. Other research has shown that Alzheimer’s and Parkinson’s diseases might elicit – or be caused in part by – changes in blood flow to certain parts of the brain, Hong said, and NIR-IIa imaging might offer a means of better understanding the role of healthy vasculature in those diseases.
"We could also label different neuron types in the brain with bio-markers and use this to monitor how each neuron performs," Hong said. "Eventually, we might be able to use NIR-IIa to learn how each neuron functions inside of the brain."

neurosciencestuff:

Scientists use lasers and carbon nanotubes to look inside living brains

Some of the most damaging brain diseases can be traced to irregular blood delivery in the brain. Now, Stanford chemists have employed lasers and carbon nanotubes to capture an unprecedented look at blood flowing through a living brain.

The technique was developed for mice but could one day be applied to humans, potentially providing vital information in the study of stroke and migraines, and perhaps even Alzheimerโ€™s and Parkinsonโ€™s diseases. The work is described in the journal Nature Photonics.

Current procedures for exploring the brain in living animals face significant tradeoffs. Surgically removing part of the skull offers a clear view of activity at the cellular level. But the trauma can alter the function or activity of the brain or even stimulate an immune response. Meanwhile, non-invasive techniques such as CT scans or MRI visualize function best at the whole-organ level; they cannot visualize individual vessels or groups of neurons.

The first step of the new technique, called near infrared-IIa imaging, or NIR-IIa, calls for injecting water-soluble carbon nanotubes into a live mouseโ€™s bloodstream. The researchers then shine a near-infrared laser over the rodentโ€™s skull.

The light causes the specially designed nanotubes to fluoresce at wavelengths of 1,300-1,400 nanometers; this range represents a sweet spot for optimal penetration with very little light scattering. The fluorescing nanotubes can then be detected to visualize the blood vesselsโ€™ structure.

Amazingly, the technique allows scientists to view about three millimeters underneath the scalp and is fine enough to visualize blood coursing through single capillaries only a few microns across, said senior author Hongjie Dai, a professor of chemistry at Stanford. Furthermore, it does not appear to have any adverse affect on innate brain functions.

"The NIR-IIa light can pass through intact scalp skin and skull and penetrate millimeters into the brain, allowing us to see vasculature in an almost non-invasive way," said first author Guosong Hong, who conducted the research as a graduate student in Daiโ€™s lab and is now a postdoctoral fellow at Harvard. "All we have to remove is some hair."

The technique could eventually be used in human clinical trials, Hong said, but will need to be tweaked. First, the light penetration depth needs to be increased to pass deep into the human brain. Second, injecting carbon nanotubes needs approval for clinical application; the scientists are currently investigating alternative fluorescent agents.

For now, though, the technique provides a new technique for studying human cerebral-vascular diseases, such as stroke and migraines, in animal models. Other research has shown that Alzheimerโ€™s and Parkinsonโ€™s diseases might elicit โ€“ or be caused in part by โ€“ changes in blood flow to certain parts of the brain, Hong said, and NIR-IIa imaging might offer a means of better understanding the role of healthy vasculature in those diseases.

"We could also label different neuron types in the brain with bio-markers and use this to monitor how each neuron performs," Hong said. "Eventually, we might be able to use NIR-IIa to learn how each neuron functions inside of the brain."

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Cypress Hill & Velvet Revolver - Paradise City

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broadwayallday:

#bwaycreative photo by @tonylear @midieaststudios #powershoot info@MidiEast.me to book yours #BroadwayAllDay #freejustty #bway100  (at MidiEast Studios)

broadwayallday:

#bwaycreative photo by @tonylear @midieaststudios #powershoot info@MidiEast.me to book yours #BroadwayAllDay #freejustty #bway100 (at MidiEast Studios)

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futurescope:

// buzzfeeds take on the damn future. nice collection of gifs but nothing more. please go on.

133 notes